Changes in Urination: Foamy or bubbly urine, urinating more/less frequently (especially at night), blood in urine, or difficulty urinating.

Swelling (Edema): Swelling in the feet, ankles, legs, hands, or puffiness around the eyes.

Severe Fatigue and Weakness: Due to anemia caused by decreased EPO hormone production from damaged kidneys.

Skin Rash and Severe Itching: Caused by waste buildup (uremia) in the bloodstream.

Metallic Taste in Mouth or Ammonia Breath: Caused by excess waste products in the blood.

Shortness of Breath: Fluid buildup in the lungs or anemia.

Flank/Back Pain: Pain in the lower back or side near the kidneys.

Dizziness and Trouble Concentrating: Due to anemia affecting oxygen supply to the brain.

Nausea and Vomiting: Toxins accumulating in the body.

Cold Chills: Feeling cold even in a warm environment (often secondary to anemia).